Ligand binding to a non-covalent binding in solution.
2.
Alternative procedures describe unspecific covalent binding and adhesive immobilization.
3.
This results in covalent binding of the electrophile.
4.
The target was to identify the non-covalent binding between hemoglobin and relevant chemicals.
5.
This metabolite has a different liver toxicity : in particular, it " inhibits " the CYP1B enzymes by covalent binding.
6.
Reversible covalent binding of IPA-3 to the PAK1 regulatory domain prevents GTPase docking and the subsequent switch to a catalytically active state.
7.
Note the contrast to the phenylisothiocyanate covalent binding site locations as compared to the one on p-Isococ, a non-phenyltropane cocaine analogue.
8.
Covalent binding of disulfiram to the thiol blocks the binding of one of the cysteine residues with iodoacetamide, thereby inactivating the enzyme and significantly lowering catalytic activity.
9.
Covalent binding of the aglycone portions of several carboxylic acid ( ester ) glucuronides is known to occur to nucleophilic sites on serum albumin via transacylation reactions, for example.
10.
Also, their mechanism of action involves covalent binding of the activated drug to the enzyme, resulting in a duration of action that exceeds their plasma half-life.
मोबाइल